TABLE 3. Performance Metrics for Using Shannon and Sample Entropies to Grade Hepatic Steatosis as Mild, Moderate, and Severe.

	Mild		Moderate		Severe
Parameter	Shannon entropy	Sample entropy	Shannon entropy	Sample entropy	Shannon entropy	Sample entropy
Cutoff value	3.71	1.78	3.74	1.82	3.75	1.82
Sensitivity, %	69.07	79.38	80.50	88.51	74.19	76.96
Specificity, %	74.60	78.84	83.93	80.36	86.96	86.96
Accuracy, %	72.73	79.02	81.82	85.31	77.27	79.37
LR+	2.72	3.75	5.01	4.51	5.69	5.90
LR−	0.41	0.26	0.23	0.14	0.30	0.26
PPV, %	58.26	65.81	88.61	87.50	94.71	94.89
NPV, %	82.46	88.17	73.44	81.82	51.72	54.55
AUROC	0.80	0.86	0.89	0.90	0.87	0.88
ROC comparison by DeLong test
Area Difference	0.060		0.016		0.014
SE	0.016		0.013		0.015
Z Value	13.61		1.61		0.89
P Value	0.000		0.204		0.346

LR== positive likelihood ratio; LR− = negative likelihood ratio; PPV = positive predictive value; NPV = negative predictive value; AUROC = area under the receiver operating characteristic curve; SE = standard error.