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. 2021 Oct 27;11:735704. doi: 10.3389/fonc.2021.735704

Table 2.

Knowledge of and compliance with guideline recommendations.

No. Recommendations N (%) p-value
Knowledge Compliance
1 The presence of detrusor muscle in the specimen is necessary for the NMIBC patients having had initial TURBT 786 (97.40) / /
2 Perform a single postoperative instillation of intravesical chemotherapy after TURBT 780 (96.77) / /
Further chemotherapy instillations
3 Not recommended for low-risk NMIBC patients 32 (3.97) 13 (1.61) <0.001
4 Provide induction and maintenance chemotherapy instillations for intermediate-risk NMIBC patients 735 (91.99) 743 (92.99) 0.243
5 Provide induction and maintenance chemotherapy instillations for high-risk NMIBC patients / 704 (89.00) /
BCG immunotherapy
6 Not recommended for low-risk NMIBC patients 336 (43.08) 307 (39.36) 0.181
7 Provide induction and maintenance chemotherapy instillations for intermediate-risk NMIBC patients 513 (66.97) 518 (67.62) 0.685
8 Provide induction and maintenance chemotherapy instillations for high-risk NMIBC patients 608 (79.89) 614 (80.68) 0.451
9 Indications for a second TURBT
After incomplete initial TURBT 640 (79.60) 542 (67.41) <0.001
There is no muscular layer in the first resected specimen (except for TaLG/G1 tumor and carcinoma in situ) 598 (74.38) 595 (74.00) 0.863
In T1 tumors 347 (43.16) 357 (44.40) 0.474
In G3/high-grade tumors (except for CIS) 456 (56.72) 441 (54.85) 0.228
Pathology analysis results of initial TURBT failed to determine stage or risk grading 485 (60.32) 443 (55.10) 0.001
10 Indications for radical cystectomy
High-grade T1 with histological variation (micropapillary, sarcoma, small cell type) 466 (58.54) 398 (50.00) <0.001
High-grade T1 with lymphatic vessel infiltration, multiple and/or large high-grade T1, high-grade T1 with bladder/prostate CIS 654 (82.16) 634 (79.65) 0.111
Pathology analysis results of a second TURBT is still high-grade T1 491 (61.68) 545 (68.47) <0.001
High-grade NMIBC with early recurrence within 3 months 532 (66.83) 542 (68.09) 0.440
NMIBC involving the bladder diverticulum 331 (41.58) 384 (48.24) <0.001
High-risk NMIBC patients with BCG failure 590 (74.12) 526 (66.08) <0.001