Figure 1. Signaling pathways in T-lymphocyte activation. LAT, linker of activated T cells; DAG, diacylglycerol; IP3, inositol triphosphate; PLC-γ, phosphoinositide phospholipase C; SLP-76, lymphocyte cytosolic protein; PKCθ, protein kinase C; RAS, family of GTP-binding proteins; LCK, lymphocyte-specific protein tyrosine kinase; FYN, member of Src tyrosine kinase; ZAP-70, ζ chain-associated protein kinase of 70 kDa.
