1. |
Stromal factors/growth factors/cytokines involved in CSC self-renewal, proliferation, maintenance, migration |
IL-6, IL-8, TGF-β1, VEGFA, EGF, FGF2, CXCL12, PDGFD, IGF2, BMI1, HGF, TNF-α |
2. |
Genes related to Hypoxia and EMT- the mechanism involved in CSC expansion |
HIF1A, ARNT, EPAS1, TAZ, SIAH1, SNAI1, SNAI2, TWIST1, SOX9, ZEB1, CDH1, CDH2, VIM |
3. |
Extracellular proteins involved in CSC expansion, self-renewal, maintenance of CSC niche |
HAS1, HAS2, TNC, SPP1, LUM, SPARC, POSTN, COL6A3, S100A4, SDC1 |
4. |
Signaling molecules involved in CSC expansion, self-renewal, maintenance |
SMAD2, SMAD3, SMAD4, WNT3A, WNT5A, JAG1 |
5. |
Chemokines/chemokine receptors involved in CSC self-renewal, maintenance |
CXCR2, CXCR1, PPBP |