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. 2021 Sep 2;15:1281. doi: 10.3332/ecancer.2021.1281

Table 4. Studies reporting use of Pazopanib in uncommon/unclassified STS subtypes.

Author No. of
patients (n)
HPE subtype ORR PFS (months) mOS (months)
Frezza et al [10] 18 Epithelioid sarcoma 0% 3 NR
Touati et al [8] 11 Epithelioid sarcoma 11.1% 3.8 10.8
Stacchiotti et al [37] 30 ASPS 24.2% 13.6 NR
Kim et al [16] 6 ASPS 16.7% 5.5 NR
Stacchiotti et al [38] 26 Extraskeletal myxoid chondrosarcoma 18% 2-year
PFS – 40%
NR
Kollár et al [18] 52 Angiosarcoma, haemangioendothelioma Intimal sarcoma 20%
20%
100%
3
NR
NR
9.9
NR
NR
Martin-Broto et al [17] 31 Solitary fibrous tumour 58% 9.8 49.8
Our study 33 Haemangiopericytoma, pleomorphic RMS (adult type), MFS, spindle cell sarcoma, MPNST, ASPS, haemangioendothelioma, epethelioid sarcoma, clear cell sarcoma, UPS. Retroperitoneal sarcoma, angiosarcoma 27.2% 10.3 17.8

NR, Not reported; HPE, Histopathological examination; ORR, Objective response rate; PFS, Progression free survival; OS, Overall survival; ASPS, Alveolar soft part sarcoma; MPNST, Malignant peripheral nerve sheath tumour; UPS, Undifferentiated pleomorphic sarcoma; RMS, Rhabdomyosarcoma