Table 2. Comparison of PFS and OS among different prognostic variables.
| Prognostic variables | Features | 2-year PFS (95% CI) | p value | 2-year OS (95% CI) | p value | |
|---|---|---|---|---|---|---|
| Age | ≤57 years | 40 | 66.0 (43.9–81.1) | 0.55 | 74.6 (54.7–86.7) | 0.56 |
| >57 years | 40 | 66.5 (46.3–80.6) | 77.9 (58.4–89.0) | |||
| Sex | Male | 49 | 64.7 (45.5–78.5) | 0.80 | 81.5 (64.4–90.9) | 0.46 |
| Female | 31 | 68.3 (44.4–83.6) | 68.3 (45.6–83.2) | |||
| Location | Lower | 38 | 60.3 (38.1–76.7) | 0.35 | 73.8 (53.4–86.4) | 0.21 |
| Middle & Upper | 42 | 70.7 (50.8–83.8) | 78.8 (60.0–89.4) | |||
| Clinical N status | N0 N1 | 60 | 70.9 (54.8–82.2) | 0.29 | 82.1 (68.0–90.4) | 0.11 |
| N2 N3 | 20 | 46.9 (17.6–71.8) | 53.0 (20.7–77.4) | |||
| Radiological tumour length | ≤5.5 cm | 41 | 66.7 (47.7–80.1) | 0.35 | 78.8 (58.0–90.1) | 0.24 |
| >5.5 cm | 39 | 67.1 (43.8–82.5) | 72.4 (53.3–84.7) | |||
| PTV length | ≤15.6 cm | 40 | 61.5 (40.8–76.8) | 0.70 | 74.0 (53.6–86.4) | 0.94 |
| >15.6 cm | 40 | 72.1 (49.7–85.8) | 76.6 (56.4–88.4) | |||
| PTV volume | ≤424.5 cc | 41 | 68.8 (49.3–82.1) | 0.94 | 81.5 (62.2–91.5) | 0.26 |
| >424.5 cc | 39 | 63.0 (39.3–79.6) | 68.5 (47.6–82.5) | |||
| CROSS eligible | Yes | 47 | 74.3 (56.0–85.9) | 0.05 | 78.6 (60.9–89.0) | 0.14 |
| No | 33 | 54.8 (31.7–72.9) | 72.7 (50.4–86.2) | |||
| TRG class | 0, 1 | 47 | 73.1 (52.9–85.7) | 0.09 | 76.1 (57.2–87.5) | 0.45 |
| 2, 3 | 33 | 58.2 (36.4–74.8) | 76.5 (56.2–88.3) | |||
| ypN status | Node negative | 59 | 70.6 (53.7–82.3) | 0.09 | 85.7(72.0-93.0) | 0.03 |
| Node positive | 21 | 54.0 (26.4–75.3) | 48.4 (20.6–71.7) | |||
| pCR | Yes | 33 | 77.0 (53.1–89.8) | 0.06 | 82.0 (61.3–92.3) | 0.21 |
| No | 47 | 58.2 (39.2–73.2) | 72.1 (53.6–84.2) | |||
PFS, Progression free survival; OS, Overall survival; CI, Confidence interval; HR, Hazard ratio; PTV, Planning target volume; pCR, Pathological complete response; TRG, Tumour regression grade; NA, Not applicable