Table 1.
A number of pharmacological activities of quercetin reported in recent studies.
| Dose | Model | Administration | Activity | Ref. |
|---|---|---|---|---|
| 25 μM | MCF-7 and MDA-MB-231 | Direct treatment | Apoptosis induction and anticancer effect | [129] |
| 20 μM | Human umbilical vein endothelial cells (HUVECs) | Direct treatment | Autophagy and promoted cell survival | [130] |
| 5.7 μM (DPPH assay) | Erythrocytes | Direct treatment | ROS and free radical scavenging activity | [131] |
| 100 mg kg−1 | C57BL/6J mice on ethanol-containing Lieber De Carli liquid diets | Gavage | Suppressed autophagic flux, decreased liver injury by ethanol consumption | [132] |
| 100 mg kg−1 | Streptococcus suis infected mice | Subcutaneous | Antimicrobial effect against Streptococcus suis | [133] |
| 100 mg kg−1 | Chronic ethanol feeding C57BL/6J mice | Oral | Decreased fat accumulation in liver (ethanol induced) | [134] |
| 30 mg kg−1 | STZ-induced diabetic rats | Intraperitoneal | Higher insulin levels, improved dyslipidemia, reduced serum blood glucose levels, decreased oxidative stress | [135] |
| 100-200 mg kg−1 | STZ-induced diabetic Wistar rats | Oral | Controlled insulin resistance, reduced blood sugar, pancreatic cells protection | [136] |
| 5-20 mg kg−1 | STZ-induced diabetic rats | Oral | Controlled body weight and blood glucose, performance in the Morris water test | [137] |
| 40 mg kg−1 | STZ-induced diabetic mice in the Morris water maze task | Oral | Enhanced the time spent by mice in the target quadrant in the Morris water maze task | [138] |