Table 2.
Single factor analysis of PFS.
| Variable | PFS | ||||
|---|---|---|---|---|---|
| Mean (months) | 95% confidence interval | Chi-square | Log-rank P value | ||
| Lower bound | Upper bound | ||||
| Age | 0.038 | 0.845 | |||
| ≤55 | 18.21 | 13.725 | 22.685 | ||
| >55 | 17.75 | 10.770 | 24.730 | ||
| Gender | 0.022 | 0.881 | |||
| Male | 18.51 | 13.342 | 23.683 | ||
| Female | 15.06 | 12.016 | 18.095 | ||
| Lymph node metastasis | 3.218 | 0.073 | |||
| N0 | |||||
| N1 | |||||
| Degree of tumor | 3.126 | 0.077 | |||
| Low | 14.58 | 9.357 | 19.803 | ||
| Medium/high | 21.88 | 17.979 | 25.771 | ||
| Tumor size (cm) | 1.126 | 0.289 | |||
| ≤4 | 14.58 | 11.447 | 22.286 | ||
| >4 | 21.88 | 15.988 | 24.699 | ||
| Total-CTCs -1/5 mL | 0.177 | 0.674 | |||
| ≤3 | 18.735 | 14.011 | 23.459 | ||
| >3 | 17.500 | 11.682 | 23.318 | ||
| E-CTCs-1/5 mL | 0.614 | 0.433 | |||
| 0 | 17.18 | 12.588 | 21.762 | ||
| ≥1 | 21.17 | 16.097 | 26.236 | ||
| E/M-CTCs-1/5 mL | 1.154 | 0.283 | |||
| <2 | 10.45 | 8.088 | 12.818 | ||
| ≥2 | 19.67 | 15.488 | 23.858 | ||
| M-CTCs-1/5 mL | 0.987 | 0.320 | |||
| 0 | 16.66 | 11.923 | 21.399 | ||
| ≥1 | 21.17 | 16.097 | 26.236 | ||
| Total-CTCs -2/5 mL | 7.354 | 0.007∗∗ | |||
| ≤3 | 22.60 | 19.997 | 25.203 | ||
| >3 | 11.07 | 6.835 | 15.311 | ||
| E-CTCs-2/5 mL | 4.591 | 0.032∗ | |||
| 0 | 20.41 | 16.802 | 24.017 | ||
| ≥1 | 11.25 | 4.232 | 18.268 | ||
| E/M-CTCs-2/5 mL | 2.181 | 0.140 | |||
| <2 | 21.78 | 17.671 | 25.884 | ||
| ≥2 | 15.42 | 10.216 | 20.628 | ||
| M-CTCs-2/5 mL | 2.718 | 0.099 | |||
| 0 | 20.73 | 16.678 | 24.772 | ||
| ≥1 | 12.75 | 8.317 | 17.183 | ||
| Dynamic of total CTCs | 8.116 | 0.004∗∗ | |||
| Decrease or unchanging | |||||
| Increase | |||||
| Dynamic of E-CTCs | 1.659 | 0.198 | |||
| Decrease or unchanging | 19.41 | 15.573 | 23.254 | ||
| Increase | 12.67 | 2.859 | 22.474 | ||
| Dynamic of E/M-CTCs | 0.549 | 0.459 | |||
| Decrease or unchanging | 19.11 | 14.484 | 23.743 | ||
| Increase | 12.95 | 8.821 | 17.084 | ||
| Dynamic of M-CTCs | 5.937 | 0.015∗ | |||
| Decrease or unchanging | 21.30 | 17.887 | 24.713 | ||
| Increase | 11.33 | 6.035 | 16.632 | ||
∗∗ P < 0.01 (2-tailed); ∗P < 0.05 (2-tailed).