Table 4.
Relationships between 5-Aminolevulinic Acid-induced Intraoperative Hypotension and Clinical Backgrounds in Urological Surgery Patients.
| SBP < 80mmHg | SBP ≥80mmHg | P-value | |
|---|---|---|---|
| Number | 10 | 15 | |
| Age (yr) ≥80 | 1 (10.0%) | 2 (13.3%) | 1.000 |
| Sex | 0.626 | ||
| Female | 1 (10.0%) | 3 (20.0%) | |
| Male | 9 (90.0%) | 12 (80.0%) | |
| BMI (kg/m2) ≥25 | 3 (30.0%) | 2 (13.3%) | 0.358 |
| Anesthesia | 0.075 | ||
| GA | 5 (50.0%) | 2 (13.3%) | |
| SA | 5 (50.0%) | 13 (86.7%) | |
| Comorbidity | 8 (80.0%) | 11 (73.3%) | 1.000 |
| Hypertension | 8 (80.0%) | 4 (26.7%) | 0.015 |
| Diabetes mellitus | 4 (40.0%) | 5 (33.3%) | 1.000 |
| Heart disease | 3 (30.0%) | 3 (20.0%) | 0.653 |
| Hyperlipidemia | 3 (30.0%) | 3 (20.0%) | 0.653 |
| CKD | 3 (30.0%) | 4 (26.7%) | 1.000 |
| Stroke | 0 (0.0%) | 1 (6.7%) | 1.000 |
| Antihypertensives | 8 (80.0%) | 4 (26.7%) | 0.015 |
| RAS inhibitor | 4 (40.0%) | 4 (26.7%) | 0.667 |
| Ca antagonist | 3 (30.0%) | 4 (26.7%) | 1.000 |
| β-Blocker | 1 (10.0%) | 0 (0.0%) | 0.400 |
| Pathology | 0.353 | ||
| Ta | 3 (30.0%) | 8 (53.3%) | |
| T1 | 3 (30.0%) | 4 (26.7%) | |
| CIS | 2 (20.0%) | 3 (20.0%) | |
| Others | 2 (20.0%) | 0 (0.0%) |
Note: Data are presented as numbers (proportion). The number of 5-aminolevulinic acid-pretreated patients for analysis was 25, because 1 patient did not proceed with the surgery due to a persistent SBP of <80 mmHg.
Abbreviations: SBP <80mmHg, patients who had intraoperative hypotension below 80 mmHg; SBP ≥80mmHg, patients who had intraoperative minimum systolic blood pressure above 80 mmHg; GA, general anesthesia; SA, spinal anesthesia; CKD, chronic kidney disease (estimated glomerular filtration rate <60mL/min/1.73m2); RAS, renin-angiotensin system.