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Pathways associated with erythrocytosis
(A) The genes involved in the hypoxia-inducible factor (HIF) – erythropoietin (EPO) pathway in the kidneys. (B) Genes involved in the EPO – erythropoietin receptor (EPOR) signalling pathway in erythroid progenitors. (C) Genes affecting haemoglobin-oxygen affinity in erythrocytes.
