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. 2021 Oct 14;16(11):2703–2717. doi: 10.1016/j.stemcr.2021.09.006

Figure 6.

Figure 6

Evaluation of motor functional recovery

(A) Hindlimb motor function was evaluated weekly for 63 days after SCI (54 days after transplantation) by BMS scores in the LOTUS group, the control group and the PBS group (LOTUS group; n = 15, control group; n = 13, PBS group; n = 10).

(B) The rotarod test was performed 54 days after transplantation, and quantitatively analysis of total run time was evaluated (LOTUS group; n = 15, control group; n = 13, PBS group; n = 10).

(C) Treadmill gait analyses using a DigiGait system were examined 54 days after transplantation, and quantitative analyses of the stride length and stance angle were performed (LOTUS group; n = 15, control group; n = 13, PBS group; n = 10).

(D) Hindlimb coordination was analyzed by phase dispersions as the diagonal/hindlimbs coordination in DigiGait analyses (LOTUS group; n = 15, control group; n = 13, PBS group; n = 10). Values are the mean ± SEM; ∗p < 0.05, ∗∗p < 0.01. Statistical analysis was performed using two-way repeated-measures ANOVA with Tukey's test in the analysis of the BMS score and one-way ANOVA followed by the Tukey-Kramer test in the rotarod test and DigiGait analyses.