TABLE 1.

In situ hybridization pattern (%) of S-phase nuclei from Manca cell line

Cosmid clones	SS	SD	DD
FRA7H region
176g10	32	35	33
118h6	31	34	34
159c12	33	35	32
Control regiona
cNH24	77	10	13
cW44	73	12	15

^aThe replication time of these clones was determined previously by FISH and by cell-fractionation-based methods in the Manca cell line (36).