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. 2021 Nov 10;11:22006. doi: 10.1038/s41598-021-01365-5

Table 1.

Baseline characteristics between bisoprolol and placebo groups.

Characteristics Bisoprolol (N = 57) Placebo (N = 55) P value
Age (years) 62.5 ± 11.8 64.4 ± 13.1 0.416
Male 37 (67.3%) 27 (50.9%) 0.177
BMI (kg/m2) 21.5 ± 4.3 21.3 ± 4.1 0.876
DM 10 (18.2%) 7 (13.2%) 0.600
DM requiring insulin therapy 5 (9.1%) 3 (5.7%) 0.716
Hypertension 30 (54.5%) 23 (43.4%) 0.256
History of stroke 3 (5.5%) 2 (3.8%) 1.000
Coronary artery disease 4 (7.0%) 4 (7.3%) 1.000
Heart failure 0 (0%) 0 (0%)
LVEF (%) 64.7 ± 8.3 67.3 ± 8.1 0.104
ASA score
ASA I 24 (42.1%) 30 (54.5%) 0.407
ASA II 26 (45.6%) 19 (34.5%)
ASA III 7 (12.3%) 6 (10.9%)
Hemoglobin (gm/dL) 11.8 ± 1.8 12.2 ± 2.5 0.411
Creatinine (mg/dL) 1.2 ± 1.2 1.1 ± 1.2 0.616
Antiplatelet 15 (27.3%) 10 (18.9%) 0.364
Statin 17 (30.9%) 12 (22.6%) 0.389
ACEI/ARB 6 (10.9%) 6 (11.3%) 1.000
Median duration of preoperative assigned therapy (days) 3 ± 4 4 ± 2 0.669

ACEI/ARB angiotensin converting enzyme inhibitor/Angiotensin receptor blocker, BMI body mass index, DM diabetes mellitus, hs-TNT high-sensitive troponin-T, LVEF left ventricular ejection fraction.