Table 3.
Prematurity, low birth weight, admission to NICU/NCU, and hospitalization in fresh and frozen cycles
Outcome | Fresh cycles | Frozen cycles | Total | |||
---|---|---|---|---|---|---|
Follitropin delta | Follitropin alfa | Follitropin delta | Follitropin alfa | Follitropin delta | Follitropin alfa | |
N | 308 | 310 | 125 | 130 | 433 | 440 |
Preterm birth | ||||||
All | ||||||
<32 weeks | 8 (2.6) | 6 (1.9) | 1 (0.8) | 1 (0.8) | 9 (2.1) | 7 (1.6) |
32–36 weeks | 37 (12.0) | 35 (11.3) | 21 (16.8) | 28 (21.5) | 58 (13.4) | 63 (14.3) |
Singletons | ||||||
<32 weeks | 4 (1.4) | 1 (0.4) | 1 (1.1) | 1 (1.1) | 5 (1.4) | 2 (0.5) |
32–36 weeks | 21 (7.6) | 18 (6.5) | 3 (3.3) | 6 (6.7) | 24 (6.5) | 24 (6.6) |
Multiples | ||||||
<32 weeks | 4 (12.5) | 5 (14.7) | 0 | 0 | 4 (6.2) | 5 (6.8) |
32–36 weeks | 16 (50.0) | 17 (50.0) | 18 (54.5) | 22 (55.0) | 34 (52.3) | 39 (52.7) |
Low birth weight | ||||||
All | ||||||
<1500 g | 8 (2.6) | 3 (1.0) | 0 | 1 (0.8) | 8 (1.8) | 4 (0.9) |
1500–2499 g | 35 (11.4) | 35 (11.3) | 14 (11.2) | 28 (21.5) | 49 (11.3) | 63 (14.3) |
Singletons | ||||||
<1500 g | 4 (1.4) | 0 | 0 | 1 (1.1) | 4 (1.1) | 1 (0.3) |
1500–2499 g | 19 (6.9) | 19 (6.9) | 1 (1.1) | 3 (3.3) | 20 (5.4) | 22 (6.0) |
Multiples | ||||||
<1500 g | 4 (12.5) | 3 (8.8) | 0 | 0 | 4 (6.2) | 3 (4.1) |
1500–2499 g | 16 (50.0) | 16 (47.1) | 13 (39.4) | 25 (62.5) | 29 (44.6) | 41 (55.4) |
Admission to NICU/NCUa | ||||||
All | 29 (9.4) | 30 (9.7) | 17 (13.6) | 22 (16.9) | 46 (10.6) | 52 (11.8) |
Hospitalizationb | ||||||
All | 7 (2.3) | 12 (3.9) | 3 (2.4) | 3 (2.3) | 10 (2.3) | 15 (3.4) |
Values are n (%), unless otherwise stated. Singleton and multiple status were based on the number of intrauterine viable fetuses at the ongoing pregnancy visit
aWithin 24 h after birth
bBetween 24 h and 4 weeks after birth
N total number of live-born neonates, n number of live-born neonates with observations, NCU neonatal care unit, NICU neonatal intensive care unit