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. 2021 Jul 13;38(10):2651–2661. doi: 10.1007/s10815-021-02271-5

Table 3.

Prematurity, low birth weight, admission to NICU/NCU, and hospitalization in fresh and frozen cycles

Outcome Fresh cycles Frozen cycles Total
Follitropin delta Follitropin alfa Follitropin delta Follitropin alfa Follitropin delta Follitropin alfa
N 308 310 125 130 433 440
Preterm birth
All
<32 weeks 8 (2.6) 6 (1.9) 1 (0.8) 1 (0.8) 9 (2.1) 7 (1.6)
32–36 weeks 37 (12.0) 35 (11.3) 21 (16.8) 28 (21.5) 58 (13.4) 63 (14.3)
Singletons
<32 weeks 4 (1.4) 1 (0.4) 1 (1.1) 1 (1.1) 5 (1.4) 2 (0.5)
32–36 weeks 21 (7.6) 18 (6.5) 3 (3.3) 6 (6.7) 24 (6.5) 24 (6.6)
Multiples
<32 weeks 4 (12.5) 5 (14.7) 0 0 4 (6.2) 5 (6.8)
32–36 weeks 16 (50.0) 17 (50.0) 18 (54.5) 22 (55.0) 34 (52.3) 39 (52.7)
Low birth weight
All
<1500 g 8 (2.6) 3 (1.0) 0 1 (0.8) 8 (1.8) 4 (0.9)
1500–2499 g 35 (11.4) 35 (11.3) 14 (11.2) 28 (21.5) 49 (11.3) 63 (14.3)
Singletons
<1500 g 4 (1.4) 0 0 1 (1.1) 4 (1.1) 1 (0.3)
1500–2499 g 19 (6.9) 19 (6.9) 1 (1.1) 3 (3.3) 20 (5.4) 22 (6.0)
Multiples
<1500 g 4 (12.5) 3 (8.8) 0 0 4 (6.2) 3 (4.1)
1500–2499 g 16 (50.0) 16 (47.1) 13 (39.4) 25 (62.5) 29 (44.6) 41 (55.4)
Admission to NICU/NCUa
All 29 (9.4) 30 (9.7) 17 (13.6) 22 (16.9) 46 (10.6) 52 (11.8)
Hospitalizationb
All 7 (2.3) 12 (3.9) 3 (2.4) 3 (2.3) 10 (2.3) 15 (3.4)

Values are n (%), unless otherwise stated. Singleton and multiple status were based on the number of intrauterine viable fetuses at the ongoing pregnancy visit

aWithin 24 h after birth

bBetween 24 h and 4 weeks after birth

N total number of live-born neonates, n number of live-born neonates with observations, NCU neonatal care unit, NICU neonatal intensive care unit