Table 5.

The best model prediction of the interaction between the PIK3CA gene rs9838117 and ERBB2 gene rs1058808 sites and the clinical data of subjects

Model	Training balanced accuracy	Testing balanced accuracy	χ2	OR (95%CI)	P	Cross-validation consistency
rs1058808	0.5666	0.5415	0.86	1.40 (0.69–2.87)	0.35	6/10
OC family history, rs9838117	0.5906	0.5500	1.53	1.64 (0.75–3.62)	0.21	8/10
Age, BMI, rs1058808	0.6092	0.5503	1.30	1.52 (0.74–3.14)	0.25	3/10
Age, BMI, rs9838117, rs1058808	0.6361	0.6233	7.55	2.77 (1.33–5.76)	<0.01	10/10
Age, BMI, OC family history, rs9838117, rs1058808	0.6538	0.6277	8.05	2.84 (1.37–5.90)	<0.01	10/10
Age, BMI, number live-born, drinking, rs9838117, rs1058808	0.6729	0.5913	4.12	2.09 (1.02–4.29)	0.04	4/10
Age, BMI, number live-born, smoking, drinking, rs9838117, rs1058808	0.6985	0.6124	6.23	2.50 (1.21–5.15)	0.01	6/10
Age, BMI, number live-born, smoking, drinking, ovarian cancer family history, rs9838117, rs1058808	0.7238	0.6377	9.36	3.10 (1.49–6.46)	<0.01	10/10

BMI, body mass index; OR, odds ratio; CI, confidence interval