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. 2021 Oct 28;8:735860. doi: 10.3389/fmed.2021.735860

Table 5.

Implementation of the ABCDEF bundle compared with previous studies before and after the COVID-19 pandemic.

Element of the ABCDEF bundle This study Referencea Referenceb Referencec
Before or after the pandemic After the COVID-19 pandemic Before the COVID-19 pandemic
Survey date 27th January
in 2021
3rd June and 1st July
in 2020
January 2015–March 2017 March–September
in 2016
Survey settings International International National (USA) International
Target ICU patients WITHOUT
COVID-19 infection
WITH
COVID-19 infection
WITH
COVID-19 infection
WITHOUT
COVID-19 infection
Number of enrolled patients (n = 627) (n = 602) (n = 262) (n = 15,226) (n = 1,521)
An entire of the ABCDED bundle (0%) (1%) (1%) (8%)
Element A, n (%) (64%) (55%) (45%) (77%) (83%)
Element B (both SAT and SBT) (17%) (10%)
    Spontaneous awakening trial, n (%) (21%) (14%) (28%) (34%) (66%)
    Spontaneous breathing trial, n (%) (29%) (16%) (28%) (36%) (67%)
Element C, n (%) (45%) (61%) (52%) (59%) (89%)
Element D, n (%) (39%) (35%) (39%) (56%) (70%)
Element E, n (%) (12%) (16%) (35%) (29%)
Element F, n (%) (16%) (30%) (16%) (63%) (67%)

Data presented as number (%). SAT, spontaneous awakening trial; SBT, spontaneous breathing trial.

a

Liu et al. (12).

b

Pun et al. (13).

c

Morandi et al. (21).