Table 3.
Univariate Cox regression analyses for consequent ICH and multivariate Cox regression analyses for ≥10 CMB events in predicting subsequent ICH (adjusted by age).
| Variable | Univariate analysis | Multivariate analysis | ||||||
|---|---|---|---|---|---|---|---|---|
| p-Value | HR | 95% CI | p-Value | HR | 95% CI | |||
| Lower | Upper | Lower | Upper | |||||
| Presence of CMBs | 0.007 | 17.00 | 2.193 | 131.785 | ||||
| 1–4 CMBs | 0.164 | 0.025 | 0.00 | 4.490 | ||||
| 5–9 CMBs | 0.729 | 1.314 | 0.280 | 6.160 | ||||
| ≥10 CMBs | <0.001 | 26.311 | 5.679 | 121.90 | 0.031 | 1.311 | 0.679 | 8.190 |
| Male | 0.062 | 0.336 | 0.106 | 1.058 | ||||
| Age | 0.025 | 0.962 | 0.930 | 0.995 | 0.041 | 2.72 | 1.013 | 3.210 |
| History of coronary heart disease | 0.478 | 0.046 | 0.000 | 230.637 | ||||
| Dyslipidemia | 0.563 | 21.247 | 0.001 | 670986 | ||||
| History of ischemic stroke | 0.991 | 1.007 | 0.296 | 3.421 | ||||
| History of cerebral hemorrhage | 0.884 | 1.161 | 0.155 | 8.727 | ||||
| Atrial fibrillation | 0.812 | 0.783 | 0.105 | 5.864 | ||||
| Valvular heart disease | 0.764 | 1.360 | 0.182 | 10.148 | ||||
| Diabetes mellitus | 0.506 | 0.691 | 0.232 | 2.055 | ||||
| Hypertension | 0.301 | 0.620 | 0.122 | 3.472 | ||||
HR, hazard ratio.