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. 2021 Oct 28;8:743698. doi: 10.3389/fmed.2021.743698

Table 2.

Univariate logistic analyses to explore the association between ADL disability and different variables.

Total (n = 212) Men (n = 162) Women (n = 50)
OR (95% CI) P-value OR (95% CI) P-value OR (95% CI) P-value
Age, years 1.09 (1.05–1.14) <0.001 1.10 (1.05–1.16) <0.001 1.07 (0.97–1.18) 0.158
Women 0.74 (0.37–1.48) 0.389
Body mass index, kg/m2 0.95 (0.88–1.03) 0.187 1.00 (0.91–1.10) 0.945 0.86 (0.74–1.00) 0.051
Comorbidities
 Hypertension 1.49 (0.84–2.65) 0.175 1.45 (0.76–2.78) 0.264 1.67 (0.48–5.79) 0.422
 Cardiovascular disease 1.70 (0.93–3.10) 0.084 1.77 (0.90–3.48) 0.101 1.44 (0.39–5.38) 0.583
 Any type of cancer 1.21 (0.65–2.23) 0.553 1.23 (0.62–2.44) 0.555 0.96 (0.21–4.27) 0.951
 Diabetes 1.71 (0.93–3.14) 0.086 2.05 (1.03–4.07) 0.040 0.96 (0.24–3.78) 0.955
 Chronic obstructive pulmonary disease 1.52 (0.64–3.63) 0.341 1.54 (0.54–4.38) 0.419 1.69 (0.35–8.28) 0.517
 Chronic kidney disease 1.31 (0.62–2.81) 0.481 1.26 (0.51–3.12) 0.620 1.66 (0.40–6.88) 0.487
 Acute infection 1.46 (0.82–2.62) 0.202 1.48 (0.77–2.84) 0.243 1.20 (0.30–4.79) 0.796
MNA-SF score 0.72 (0.65–0.81) <0.001 0.74 (0.65–0.84) <0.001 0.66 (0.50–0.86) 0.003
Hemoglobin, g/L 0.99 (0.98–1.00) 0.202 0.99 (0.98–1.01) 0.346 0.98 (0.95–1.01) 0.980
Albumin, g/L 0.89 (0.84–0.94) <0.001 0.90 (0.84–0.96) 0.002 0.82 (0.71–0.96) 0.013
Body composition based on CT image
 SMI, cm2/m2 0.97 (0.93–1.01) 0.121 0.97 (0.92–1.01) 0.140 0.94 (0.85–1.05) 0.269
 SMD, HU 0.91 (0.87–0.96) <0.001 0.87 (0.81–0.92) <0.001 1.06 (0.96–1.18) 0.260
 IMAT, cm2 1.08 (1.02–1.15) 0.009 1.13 (1.05–1.22) 0.001 0.95 (0.84–1.09) 0.488
 IMAT%, % 1.05 (1.01–1.10) 0.026 1.09 (1.03–1.16) 0.005 1.00 (0.92–1.09) 0.990

HU, Hounsfield unit; IMAT, intermuscular adipose tissue; IMAT%, percentage of IMAT; MNA-SF, mini nutritional assessment short form; SMA, skeletal muscle area; SMD, skeletal muscle radiodensity, SMI, skeletal muscle index.