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. 2021 Oct 28;9:757378. doi: 10.3389/fbioe.2021.757378

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Copyright © 2021 Wang, Wang, Li, Song, Xia, Wang, Zhang, Wu and Ding.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Differentially expressed mRNA and protein markers in tumor or stroma ROIs of chemotherapy or combinational therapy patients. Boxplots of CD276 mRNA (A) and protein (B) expression in the tumor ROIs of chemotherapy or combinational therapy patients (the Mann–Whitney test p < 0.05, non-adjusted). Boxplots of IDO1 mRNA (C) and protein (D) expression in the tumor ROIs of chemotherapy or combinational therapy patients (the Mann–Whitney test p < 0.05, non-adjusted). Boxplots of CD45 (E), CD14 (F), and STING (G) expression in the stroma ROIs of chemotherapy or combinational therapy patients (the Mann–Whitney test p < 0.05, non-adjusted).