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. 2021 Oct 28;9:759535. doi: 10.3389/fped.2021.759535

Table 3.

Biomarkers in children with or without sepsis.

Biomarker Without sepsis (n = 109) Sepsis (n = 48) Z P
HBP (ng/mL) 89.95 (41.71–126.84) 151.81 (61.61–490.41) 3.47 0.001
CRP (mg/L) 5.00 (1.48–18.84) 63.10 (18.18–128.83) 6.03 <0.001
IL-6 (pg/mL) 19.50 (7.46–42.48) 64.89 (19.05–252.03) 4.81 <0.001
PCT (ng/mL) 0.16 (0.08–0.43) 1.02 (0.38–10.73) 6.32 <0.001
WBC (109/L) 9.66 (6.77–13.56) 11.70 (7.62–16.41) 1.53 0.125
N% 55.80 (34.30–72.65) 72.50 (54.18–82.95) 3.63 <0.001
D-dimer (μg/mL) 0.61 (0.38–1.05) 3.29 (0.93–10.64) 6.06 <0.001

Measurement data were presented as medians (interquartile ranges) and analyzed by the Mann–Whitney U test. HBP, heparin-binding protein; CRP, C-reactive protein; IL-6, interleukin-6; PCT, procalcitonin; WBC, white blood cell count; N%, neutrophil percentage.