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. 2021 Oct 28;9:759535. doi: 10.3389/fped.2021.759535

Table 4.

Biomarkers in children with sepsis or severe sepsis.

Biomarker Sepsis (n = 27) Severe sepsis (n = 21) Z P
HBP (ng/mL) 93.41 (34.57–194.55) 574.40 (154.61–848.30) 4.17 <0.001
CRP (mg/L) 44.70 (7.69–97.08) 63.30 (36.04–148.64) 1.63 0.103
IL-6 (pg/mL) 35.20 (17.27–123.10) 202.93 (42.50–662.04) 2.82 0.005
PCT (ng/mL) 0.46 (0.30–1.83) 4.36 (1.48–29.38) 3.50 <0.001
WBC (109/L) 12.22 (7.72–17.39) 9.99 (6.69–14.34) 1.26 0.209
N% 62.00 (45.80–76.70) 78.50 (69.90–86.10) 2.64 0.008
D-dimer (μg/mL) 0.97 (0.64–6.18) 6.94 (3.29–12.73) 3.54 <0.001

Measurement data were presented as medians (interquartile ranges) and analyzed by the Mann–Whitney U test. HBP, heparin-binding protein; CRP, C-reactive protein; IL-6, interleukin-6; PCT, procalcitonin; WBC, white blood cell count; N%, neutrophil percentage.