Table 2.
Demographics and laboratory variables in the moderately severe-to-profound SSNHL with different outcomes.
| Effective | Ineffective | P-value | |
|---|---|---|---|
| (n = 30) | (n = 40) | ||
| Baseline characteristics | |||
| Age (years) | 50.10 ± 16.97 | 51.68 ± 15.22 | 0.685 |
| Sex (male, %) | 15 (50.00) | 23 (57.50) | 0.533 |
| Hight (cm) | 168.13 ± 9.27 | 167.00 ± 8.45 | 0.596 |
| Weight (kg) | 69.12 ± 13.59 | 67.60 ± 12.00 | 0.629 |
| BMI (kg/m2) | 24.36 ± 3.73 | 24.20 ± 3.71 | 0.860 |
| Systolic blood pressure (mmHg) | 121.70 ± 16.15 | 119.98 ± 17.65 | 0.676 |
| Diastolic blood pressure (mmHg) | 77.07 ± 9.66 | 75.23 ± 10.26 | 0.445 |
| Clinical characteristics | |||
| Affected side (left, %) | 20 (66.67) | 19 (47.50) | 0.110 |
| Tinnitus (%) | 13 (43.33) | 18 (45.00) | 0.890 |
| Vertigo (%) | 3 (10.00) | 15 (37.50) | 0.009* |
| Ear fullness (%) | 3 (10.00) | 6 (15.00) | 0.536 |
| Hypertension (%) | 4 (13.33) | 8 (20.00) | 0.464 |
| Diabetes (%) | 4 (13.33) | 6 (15.00) | 0.844 |
| Time to treatment (days) | 3.57 ± 1.98 | 4.95 ± 1.54 | 0.002* |
| Hearing level (dBHL) | 75.43 ± 12.40 | 82.11 ± 12.50 | 0.030* |
| Laboratory variables | |||
| TT3 level (nmol/L) | 1.26 ± 0.19 | 1.28 ± 0.22 | 0.697 |
| TT4 level (nmol/L) | 89.08 ± 14.21 | 87.81 ± 14.98 | 0.722 |
| FT3 level (pmol/L) | 3.66 ± 0.60 | 3.79 ± 0.67 | 0.393 |
| FT4 level (pmol/L) | 16.48 ± 2.75 | 16.36 ± 2.22 | 0.844 |
| TSH level (mIU/L) | 1.50 ± 0.74 | 1.42 ± 0.83 | 0.653 |
| ΔTT3 level (nmol/L) | 0.29 ± 0.16 | 0.10 ± 0.39 | 0.006* |
| ΔTT4 level (nmol/L) | 15.21 ± 18.85 | 5.71 ± 19.87 | 0.047* |
| ΔFT3 level (pmol/L) | 1.00 ± 0.58 | 0.40 ± 0.94 | 0.002* |
| ΔFT4 level (pmol/L) | 0.35 ± 3.13 | −0.65 ± 2.93 | 0.174 |
| ΔTSH level (mIU/L) | 4.94 ± 3.21 | 1.92 ± 1.62 | <0.001* |
Data are expressed as a number with percentage for qualitative variables or mean ± standard deviation for quantitative variables. BMI, body mass index; TT3, total triiodothyronine; TT4, total thyroxine; FT3, free triiodothyronine; FT4, free thyroxine; TSH, thyroid stimulating hormone; Δ, the difference of thyroid-related hormone after treatment minus that before treatment.
The correlation was significant at the 0.05 level (P < 0.05).