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. 2021 Oct 28;12:753270. doi: 10.3389/fneur.2021.753270

Table 2.

Demographics and laboratory variables in the moderately severe-to-profound SSNHL with different outcomes.

Effective Ineffective P-value
(n = 30) (n = 40)
Baseline characteristics
Age (years) 50.10 ± 16.97 51.68 ± 15.22 0.685
Sex (male, %) 15 (50.00) 23 (57.50) 0.533
Hight (cm) 168.13 ± 9.27 167.00 ± 8.45 0.596
Weight (kg) 69.12 ± 13.59 67.60 ± 12.00 0.629
BMI (kg/m2) 24.36 ± 3.73 24.20 ± 3.71 0.860
Systolic blood pressure (mmHg) 121.70 ± 16.15 119.98 ± 17.65 0.676
Diastolic blood pressure (mmHg) 77.07 ± 9.66 75.23 ± 10.26 0.445
Clinical characteristics
Affected side (left, %) 20 (66.67) 19 (47.50) 0.110
Tinnitus (%) 13 (43.33) 18 (45.00) 0.890
Vertigo (%) 3 (10.00) 15 (37.50) 0.009*
Ear fullness (%) 3 (10.00) 6 (15.00) 0.536
Hypertension (%) 4 (13.33) 8 (20.00) 0.464
Diabetes (%) 4 (13.33) 6 (15.00) 0.844
Time to treatment (days) 3.57 ± 1.98 4.95 ± 1.54 0.002*
Hearing level (dBHL) 75.43 ± 12.40 82.11 ± 12.50 0.030*
Laboratory variables
TT3 level (nmol/L) 1.26 ± 0.19 1.28 ± 0.22 0.697
TT4 level (nmol/L) 89.08 ± 14.21 87.81 ± 14.98 0.722
FT3 level (pmol/L) 3.66 ± 0.60 3.79 ± 0.67 0.393
FT4 level (pmol/L) 16.48 ± 2.75 16.36 ± 2.22 0.844
TSH level (mIU/L) 1.50 ± 0.74 1.42 ± 0.83 0.653
ΔTT3 level (nmol/L) 0.29 ± 0.16 0.10 ± 0.39 0.006*
ΔTT4 level (nmol/L) 15.21 ± 18.85 5.71 ± 19.87 0.047*
ΔFT3 level (pmol/L) 1.00 ± 0.58 0.40 ± 0.94 0.002*
ΔFT4 level (pmol/L) 0.35 ± 3.13 −0.65 ± 2.93 0.174
ΔTSH level (mIU/L) 4.94 ± 3.21 1.92 ± 1.62 <0.001*

Data are expressed as a number with percentage for qualitative variables or mean ± standard deviation for quantitative variables. BMI, body mass index; TT3, total triiodothyronine; TT4, total thyroxine; FT3, free triiodothyronine; FT4, free thyroxine; TSH, thyroid stimulating hormone; Δ, the difference of thyroid-related hormone after treatment minus that before treatment.

*

The correlation was significant at the 0.05 level (P < 0.05).