Table 4.
Binary logistic regression analysis of the relationship between thyroid-related hormone levels and the outcome of moderately severe-to-profound SSNHL.
| Parameter | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
| OR | 95% CI | P-value | OR | 95% CI | P-value | |
| Predictor: outcome of disease | ||||||
| Age | 0.994 | 0.964–1.024 | 0.680 | |||
| Sex (male) | 0.739 | 0.285–1.914 | 0.533 | |||
| BMI | 1.012 | 0.889–1.151 | 0.858 | |||
| Systolic blood pressure | 1.006 | 0.978–1.035 | 0.671 | |||
| Diastolic blood pressure | 1.019 | 0.971–1.070 | 0.443 | |||
| Affected side (left) | 2.211 | 0.829–5.893 | 0.113 | |||
| Tinnitus | 1.070 | 0.412–2.777 | 0.890 | |||
| Vertigo | 5.400 | 1.395–20.907 | 0.015* | 3.378 | 0.677–16.855 | 0.138 |
| Ear fullness | 1.588 | 0.363–6.943 | 0.539 | |||
| Hypertension | 1.625 | 0.440–6.005 | 0.467 | 2.449 | 0.401–14.956 | 0.332 |
| Diabetes | 1.147 | 0.293–4.488 | 0.844 | 1.837 | 0.241–14.032 | 0.558 |
| Time to treatment | 0.641 | 0.477–0.861 | 0.003* | 0.697 | 0.478–1.015 | 0.060 |
| Hearing level | 0.958 | 0.921–0.997 | 0.034* | 0.956 | 0.906–1.010 | 0.107 |
| TT3 level | 0.629 | 0.063–6.253 | 0.692 | |||
| TT4 level | 1.006 | 0.974–1.040 | 0.717 | |||
| FT3 level | 0.717 | 0.336–1.527 | 0.388 | |||
| FT4 level | 1.021 | 0.840–1.241 | 0.836 | |||
| TSH level | 1.151 | 0.630–2.103 | 0.648 | |||
| ΔTT3 level | 7.605 | 1.428–40.504 | 0.017* | 1.120 | 0.049–25.606 | 0.943 |
| ΔTT4 level | 1.026 | 1.000–1.053 | 0.052 | |||
| ΔFT3 level | 2.533 | 1.300–4.937 | 0.006* | 2.048 | 0.583–7.194 | 0.263 |
| ΔFT4 level | 1.119 | 0.951–1.317 | 0.175 | |||
| ΔTSH level | 1.656 | 1.267–2.165 | <0.001* | 1.456 | 1.069–1.983 | 0.017* |
OR, odds ratio; CI, confidence interval; BMI, body mass index; TT3, total triiodothyronine; TT4, total thyroxine; FT3, free triiodothyronine; FT4, free thyroxine; TSH, thyroid stimulating hormone.
The correlation was significant at the 0.05 level (P < 0.05).