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. 2021 Oct 28;12:753270. doi: 10.3389/fneur.2021.753270

Table 4.

Binary logistic regression analysis of the relationship between thyroid-related hormone levels and the outcome of moderately severe-to-profound SSNHL.

Parameter Univariate analysis Multivariate analysis
OR 95% CI P-value OR 95% CI P-value
Predictor: outcome of disease
Age 0.994 0.964–1.024 0.680
Sex (male) 0.739 0.285–1.914 0.533
BMI 1.012 0.889–1.151 0.858
Systolic blood pressure 1.006 0.978–1.035 0.671
Diastolic blood pressure 1.019 0.971–1.070 0.443
Affected side (left) 2.211 0.829–5.893 0.113
Tinnitus 1.070 0.412–2.777 0.890
Vertigo 5.400 1.395–20.907 0.015* 3.378 0.677–16.855 0.138
Ear fullness 1.588 0.363–6.943 0.539
Hypertension 1.625 0.440–6.005 0.467 2.449 0.401–14.956 0.332
Diabetes 1.147 0.293–4.488 0.844 1.837 0.241–14.032 0.558
Time to treatment 0.641 0.477–0.861 0.003* 0.697 0.478–1.015 0.060
Hearing level 0.958 0.921–0.997 0.034* 0.956 0.906–1.010 0.107
TT3 level 0.629 0.063–6.253 0.692
TT4 level 1.006 0.974–1.040 0.717
FT3 level 0.717 0.336–1.527 0.388
FT4 level 1.021 0.840–1.241 0.836
TSH level 1.151 0.630–2.103 0.648
ΔTT3 level 7.605 1.428–40.504 0.017* 1.120 0.049–25.606 0.943
ΔTT4 level 1.026 1.000–1.053 0.052
ΔFT3 level 2.533 1.300–4.937 0.006* 2.048 0.583–7.194 0.263
ΔFT4 level 1.119 0.951–1.317 0.175
ΔTSH level 1.656 1.267–2.165 <0.001* 1.456 1.069–1.983 0.017*

OR, odds ratio; CI, confidence interval; BMI, body mass index; TT3, total triiodothyronine; TT4, total thyroxine; FT3, free triiodothyronine; FT4, free thyroxine; TSH, thyroid stimulating hormone.

*

The correlation was significant at the 0.05 level (P < 0.05).