Table 3.
RCT108 Data for Effect of Early CAG Compared With Late or No CAG on Outcomes in Patients Without ST-Segment Elevation After ROSC, Initial Shockable Rhythm
| Outcome | Certainty of evidence | OR (95% CI) | RR (95% CI) | Absolute difference, npatients/1000 (95% CI) |
|---|---|---|---|---|
| Survival at hospital discharge | Low | 0.85 (0.60–1.22) | 0.95 (0.84–1.07) | 36 fewer (119 fewer–41 more) |
| Survival at 90 d | Low | 0.89 (0.62–1.27) | 0.96 (0.85–1.08) | 26 fewer (113 fewer–50 more) |
| CPC 1–2* at ICU discharge | Low | 0.80 (0.56–1.14) | 0.90 (0.77–1.06) | 55 fewer (144 fewer–32 more) |
| CPC 1–2* at 90 d | Low | 0.94 (0.66–1.33) | 0.98 (0.86–1.11) | 14 fewer (97 fewer–60 more) |
| Percutaneous intervention frequency† | High | 1.54 (1.06–2.25) | 1.37 (1.04–1.79) | 88 more (11–176 more) |
| Coronary artery bypass grafting | Moderate | 0.87 (0.45–1.67) | 0.88 (0.48–1.60) | 10 fewer (46 fewer–157 more) |
CAG indicates coronary angiography; CPC, Cerebral Performance Category; ICU, intensive care unit; OR, odds ratio; RCT, randomized controlled trial; ROSC, return of spontaneous circulation; and RR, risk ratio.
*
CPC 1 to 2 considered a favorable neurological outcome in most studies.
†
Results are from intention-to-treat analysis. A per-protocol analysis was also performed and is included in the online CoSTR.