Table 11.
Meta-Analysis of Comparison 5: Later (Delayed) Cord Clamping at ≥30 Seconds Compared With Cut-Cord Milking for Term and Late Preterm Infants
| Outcome | Included studies | Total, n | Certainty of evidence | RR (95% CI) | Absolute difference (95% CI) or mean difference (95% CI); I2 |
|---|---|---|---|---|---|
| Neonatal mortality | Yadav et al,257 2015 | 300 | Very low | 1.00 (0.09 to 10.90) | An equal number of infants (20 fewer–20 more per 1000) died when later (delayed) cord clamping was intended than when cut-cord milking was intended |
| Hb concentration within 24 h after birth | Jaiswal et al,276 2015 Yadav et al,257 2015 |
500 | Very low | MD, –0.56 g/dL (–0.92 to –0.21); 9% | |
| Hct within 24 h after birth | Jaiswal et al,276 2015 Yadav et al,257 2015 |
500 | Very low | MD, –1.60% (–3.11 to –0.09); 45% | |
| Hb concentration within 7 d after birth | Jaiswal et al,276 2015 Yadav et al,257 2015 |
500 | Very low | MD, –0.47 g/dL (–0.81 to –0.13); 0% | |
| Hct within 7 d after birth | Jaiswal et al,276 2015 Yadav et al,257 2015 |
500 | Very low | MD, –1.11% (–2.12 to –0.09); 0% |
Hb indicates hemoglobin; Hct, hematocrit; MD, mean difference; and RR, risk ratio.