Table 12.

Meta-Analysis of Comparison 7: Later (Delayed) Cord Clamping ≥60 Seconds Versus Later (Delayed) Cord Clamping <60 Seconds for Term and Late Preterm Infants

Outcome	Included studies	Total, n	Certainty of evidence	RR (95% CI); I2	Absolute difference (95% CI) or mean difference (95% CI); I2
Neonatal mortality	Andersson et al,278 2019	231	Very low	0.10 (0.01–1.98)	30/1000 fewer infants (70 fewer–10 more per 1000) died when later (delayed) cord clamping ≥60 s was intended than when later (delayed) cord clamping <60 s was intended
Hb concentration within 24 h after birth	Katheria et al,282 2017	60	Very low		MD, 1.30 g/dL (0.14–2.46); not available*
Hyperbilirubinemia treated with phototherapy	Kc et al,279 2017 Nouraie et al,283 2019	906	Very low	1.93 (1.00–3.72); 60%	70/1000 more infants (0–204 more per 1000) had hyperbilirubinemia treated with phototherapy when later cord clamping ≥60 s was intended compared with when later cord clamping <60 s was intended
Neurodevelopmental outcomes in early childhood	Rana et al,285 2019	540	Very low	2.3 (1.44–3.78)	103/1000 more infants (34–216 more per 1000) would have ASQ-3 scores >279 when later cord clamping for ≥60 s was intended compared with when later cord clamping for <60 s was intended

ASQ-3 indicates Ages &amp; Stages Questionnaire, Third Edition; Hb, hemoglobin; MD, mean difference; and RR, risk ratio.

^*Only 1 study available.