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. 2021 Nov 11;169:229–311. doi: 10.1016/j.resuscitation.2021.10.040

Table 17.

Summary of Studies Showing Effectiveness of Various Rehydration Solutions

Rehydration solutions Outcome Studies (RCT/ non-RCT), n Subjects, n Benefit intervention, n No difference could be demonstrated, n Benefit water, n
4%–9% CED Volume/hydration status 13 (9/4) 200 7 21
4%–9% CED Vital signs 2 (2/0) 53 3
4%–9% CED Hyponatremia 7 (3/4) 86 3 9
4%–9% CED Patient satisfaction 6 (5/1) 95 36
0%–3.9% CED Volume/hydration status 6 (5/1) 53 3 13
0%–3.9% CED Vital signs 1 (1/0) 10 1
0%–3.9% CED Hyponatremia 5 (4/1) 45 4 6
0%–3.9% CED Patient satisfaction 3 (3/0) 25 16 1
Skim or low-fat cow’s milk Volume/hydration status 4 (3/1) 68 12
Skim or low-fat cow’s milk Hyponatremia 2 (1/1) 19 1 2
Skim or low-fat cow’s milk Patient satisfaction 4 (3/1) 68 26 6
Fresh coconut water Volume/hydration status 4 (4/0) 42 6
Fresh coconut water Vital signs 1 (1/0) 12 1
Fresh coconut water Hyponatremia 3 (3/0) 30 2 3
Fresh coconut water Patient satisfaction 4 (4/0) 42 4 24 1
Coconut water from concentrate Vital signs 1 (1/0) 12 1
Coconut water from concentrate Hyponatremia 1 (1/0) 12 1
Coconut water from concentrate Patient satisfaction 1 (1/0) 12 5 1
Beer with 4.5%–5% alcohol Volume/hydration status 3 (3/0) 38 7 1
Beer with 4.5%–5% alcohol Hyponatremia 1 (1/0) 16 1
Beer with 0.5%–2% alcohol Volume/hydration status 2 (2/0) 22 4
Beer with 0% alcohol Volume/hydration status 1 (1/0) 11 3

CED indicates carbohydrate-electrolyte drink; and RCT, randomized controlled trial.