FIGURE 2.

Sulfa4/22 on the release of GSDMD and inflammatory factors. (A) Results of GSDMD IF staining (n = 5): The expression level of GSDMD was relatively lower in the DMSO group, indicating the cleavage of GSDMD. While the expression of GSDMD protein was significantly up‐regulated in the MAF and Sulfa‐4/22 groups, suggesting the suppressed cleavage. (B‐C) Results of IL‐1β and IL‐18 release (n = 3): The release of inflammatory factors IL‐1β and IL‐18 was up‐regulated in the DMSO group, which was down‐regulated in the MAF and Sulfa‐4/22 groups. Comparison with the DMSO group, *p < 0.05