TABLE 1.
Comparison of physical development among the four groups in subchronic general toxicity study
| Parameters | 0 cells/head | 1 × 104 cells/head | 3 × 104 cells/head | 1 × 105 cells/head |
|---|---|---|---|---|
| Sex: Male | ||||
| Fur development | 8.00 ± 0.00 | 8.00 ± 0.00 | 8.00 ± 0.00 | 8.00 ± 0.00 |
| Incisor eruption | 10.10 ± 0.32 | 10.50 ± 0.53 | 10.30 ± 0.48 | 10.30 ± 0.48 |
| Eyelid opening | 13.90 ± 0.32 | 13.90 ± 0.57 | 13.60 ± 1.07 | 13.70 ± 0.82 |
| Sex: Female | ||||
| Fur Development | 8.00 ± 0.00 | 8.00 ± 0.00 | 8.00 ± 0.00 | 8.00 ± 0.00 |
| Incisor Eruption | 10.10 ± 0.32 | 10.20 ± 0.42 | 10.10 ± 0.32 | 10.40 ± 0.52 |
| Eyelid Opening | 13.60 ± 0.70 | 13.80 ± 0.42 | 13.70 ± 0.82 | 13.60 ± 0.70 |
Values are post‐natal day (PND) mean ± standard error of 10 rats/sex/group. The evaluation of fur development, incisor eruption and eyelid opening began on PND 8, PND 10 and PND 12, respectively.