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. 2021 Oct 23;25(22):10711–10723. doi: 10.1111/jcmm.17007

FIGURE 7.

FIGURE 7

PKM2 regulates TGF‐β/Smad2/3 and Jak2/Stat3 signalling pathways through oxidative stress. (A) Representative Western blotting (up) and quantification (down) showing the expression of the indicated signalling pathways in NRCFs treated with water or NAC (10 μM) for 2 h and with/out Ang II (1 μM) for 5 min. (B) Diagrammatic illustration of PKM2 in cardiac remodelling