Table 2.
Organs at risk dosimetric differences.
| Dose exposure | |||||
|---|---|---|---|---|---|
| Organs at risk | EBRT+SRS | EBRT+IORT | p | ||
| Mean | SD | Mean | SD | ||
| Brain V12 (no EBRT) | 49.68 | 26.7 | 16.94 | 13.33 | <0.001 |
| Brainstem Dmax | 44.06 | 17.75 | 42.91 | 16.84 | 0.228 |
| Chiasma Dmax | 28.96 | 19.09 | 27.72 | 18.5 | 0.01 |
| Left optic nerve Dmax | 15.71 | 16.23 | 14.6 | 14.66 | 0.023 |
| Right optic nerve Dmax | 19.51 | 18.69 | 19.48 | 19.48 | 0.977 |
| Left retina Dmean | 6.24 | 5.66 | 5.61 | 5.57 | <0.001 |
| Right retina Dmean | 7.28 | 6.37 | 6.5 | 5.71 | 0.008 |
| Left cochlea Dmean | 9.43 | 10.75 | 9.72 | 10.96 | 0.645 |
| Right cochlea Dmean | 10.74 | 14.9 | 11.85 | 15.35 | 0.295 |
EBRT, external beam radiotherapy; SRS, stereotactic radiosurgery; IORT, intraoperative radiotherapy; V12, volume receiving 12 Gy. The brain V12 was not added to EBRT doses due to practical reasons. Statistically significant dosimetric differences are displayed and highlighted.