Table III.
Fecundability among 7111 female pregnancy planners, by antibiotic type.a
| Exposure | No. of cycles | No. of pregnancies | Unadjusted FR (95% CI) | Adjustedb FR (95% CI) |
|---|---|---|---|---|
| No antibiotic | 23080 | 3623 | Reference | Reference |
| Penicillins | 1081 | 153 | 1.04 (0.89–1.22) | 1.09 (0.94–1.28) |
| Nitrofurantoin | 255 | 38 | 0.86 (0.62–1.18) | 0.83 (0.60–1.13) |
| Cephalosporins | 175 | 25 | 0.95 (0.66–1.37) | 0.98 (0.68–1.40) |
| Macrolides | 249 | 24 | 0.63 (0.42–0.94) | 0.70 (0.47–1.04) |
| Nitroimidazole | 137 | 20 | 0.85 (0.57–1.27) | 0.90 (0.60–1.34) |
| Sulfonamides | 101 | 17 | 1.16 (0.75–1.80) | 1.39 (0.90–2.15) |
| Quinolones | 123 | 15 | 0.86 (0.54–1.37) | 0.82 (0.52–1.30) |
| Tetracyclines | 128 | 17 | 0.84 (0.51–1.37) | 0.90 (0.55–1.48) |
| Lincosamides | 40 | 11 | 1.47 (0.88–2.47) | 1.58 (0.96–2.60) |
a
Time-varying analyses, among women completing the baseline questionnaire on or after 1 March 2016.
b
Models adjusted for age at baseline, education, income, BMI, multivitamin use, PSS score, MDI score, doing anything to improve chances of conception, intercourse frequency, geographic region, current smoking, history of STI.