Table 3 .
Longitudinal association between multimorbidity patterns and physical frailty in complete cases at six (n = 2,122) and 12 (n = 2,140) years
| Pattern | Cases | Model 1 | Model 2 | |||
|---|---|---|---|---|---|---|
| n/N | % | RRR | 95% CI | RRR | 95% CI | |
| 6-year | ||||||
| Unspecific | 90/1,121 | 8.0 | 1 (ref) | – | 1 (ref) | – |
| MSK, resp. & GI | 38/321 | 11.8 | 1.28 | 0.82–1.99 | 1.22 | 0.78–1.92 |
| Metabolic & sleep | 35/260 | 13.5 | 1.99 | 1.26–3.15 | 1.99 | 1.25–3.16 |
| Sensory & cancer | 37/193 | 19.2 | 1.31 | 0.80–2.15 | 1.36 | 0.82–2.25 |
| Cardio., anaemia & dementia | 20/112 | 17.9 | 2.34 | 1.18–4.62 | 2.25 | 1.13–4.49 |
| Psychiatric | 16/115 | 13.9 | 3.03 | 1.60–5.74 | 3.04 | 1.59–5.79 |
| 12-year | ||||||
| Unspecific | 190/1,119 | 17.0 | 1 (ref) | – | 1 (ref) | – |
| MSK, resp. & GI | 75/323 | 23.2 | 1.46 | 1.00–2.13 | 1.38 | 0.94–2.03 |
| Metabolic & sleep | 55/260 | 21.2 | 1.49 | 0.97–2.28 | 1.43 | 0.93–2.19 |
| Sensory & cancer | 61/204 | 29.9 | 1.99 | 1.12–3.52 | 1.87 | 1.05–3.35 |
| Cardio., anaemia & dementia | 27/116 | 23.3 | 5.31 | 1.75–16.13 | 4.81 | 1.59–14.60 |
| Psychiatric | 27/118 | 22.9 | 2.74 | 1.54–4.89 | 2.62 | 1.45–4.72 |
Notes: MSK, resp. & GI = musculoskeletal, respiratory & gastrointestinal diseases; metabolic & sleep = metabolic & sleep disorders; sensory & cancer = sensory impairments & cancer; cardio., anaemia & dementia = cardiovascular diseases, anaemia & dementia. Missing observations in 6-year analysis: education (n = 1), civil status (n = 2), alcohol consumption (n = 8) and smoking status (n = 11). Missing observations in 12-year analysis: education (n = 1), civil status (n = 1), alcohol consumption (n = 9) and smoking status (n = 10). Model 1: adjusted for age, sex and education. Model 2: adjusted for age, sex, education, civil status, smoking status and alcohol consumption.