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. 2021 Oct 28;12:737427. doi: 10.3389/fimmu.2021.737427

Figure 4.

Figure 4

Comparison of distances between CSR breaks and nearest activation-induced deaminase (AID) target sites. Distances between the position of DNA breaks and nearby WRCY sites were scored in either junctions from wild type B-cells, AID-deficient B-cells, or a control reference distribution of random breaks (4,000 junctions). An approximate permutation distribution test built from 100,000 random permutations was performed. ns, non significant.