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. 2021 Oct 17;11(20):9884–9903. doi: 10.7150/thno.63202

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Genomic determinants of inflammasome clusters. The layout of TumorMap was conducted from sample Euclidean similarity based on the five inflammasome-signaling-related scores, and similar samples were grouped. Distinct genomic features (Mutation, SCNA, and dysregulated coding genes) are also depicted. Differential enrichment or deletion of SCNA drivers, mutation drivers, and coding mRNAs in each cluster compared to all other clusters is shown. IC, inflammasome complex; SCNA, somatic copy-number alteration; UCG, upregulated coding gene; DCG, downregulated coding gene.