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. 2021 Oct 11;11(20):9833–9846. doi: 10.7150/thno.62449

Figure 1.

Figure 1

The characterization of PICASSO. (A) Representative the preparation of PICASSO. (B) Size distribution and surface charge. (C) TEM images of PICASSO in simulated tumor conditions. (D) Plasmid condensation assay. Lane 1-9: DNA marker, CRISRPa plasmid (10 kb), PPT35@plasmid polyplexes at different polymer to plasmid weight ratios (0.5:1, 1:1, 2:1, 5:1, 10:1, 15:1), NON and PICASSO (shell:core:plasmid, 25:10:1). (E) Cytotoxicity of different groups by MTT assay.