. 2021 Oct 28;9:758217. doi: 10.3389/fcell.2021.758217

TABLE 3.

Indications and contraindications for scaffold-based meniscal substitutes and meniscal allograft transplantation.

	Scaffold-based meniscal substitution	Meniscal allograft transplantation
Indications	Clinical symptoms	Clinical symptoms
	s/p extensive partial meniscal resection	s/p sub-/total meniscal resection
	Stable meniscal rim	Insufficient meniscal rim
	Intact meniscal roots	Insufficient meniscal roots
	Chronic partial meniscal defect
Contraindications	Age: > 50 years^a	Age: > 50 years^a
	BMI: > 35^a	BMI: > 35^a
	Insufficient meniscal rim	Outerbridge grade III, IV
	Insufficient meniscal roots	Fairbank grade > 2
	Knee instability	Joint space narrowing
	Limb malalignment	Knee instability
	Allergies to animal derived products	Limb malalignment
	ICRS grade > 3	Active infection
	Active infection	Autoimmune diseases
	Autoimmune diseases	Inflammatory arthritis
	Inflammatory arthritis	Smoker^a
	Smoker^a

ICRS, International cartilage repair society; s/p, status post.

^aRelative contraindication.