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. 2021 Oct 28;11:721764. doi: 10.3389/fonc.2021.721764

Table 3.

Clinical characteristics of patients who progressed during follow-up.

rhTPO group Non-rhTPO group
Patient 1 Patient 2 Patient 3 Patient 4 Patient 5 Patient 6 Patient 6
Age (years) 41 58 67 46 62 52 48
Sex M M F F F F M
R-IPSS Int-1 Int-1 Int-1 Int-1 Low Int-1 Low
Baseline
 Karyotype 46,XY [20] 46,XY [20] 46,XX [20] 46,XX [20] 46,XX [20] 46,XX [20] 46,XY [20]
 Bone marrow blasts (%) <5 <5 <2 <5 <5 <5 <2
 ANC (×109/μl) 1.25 2.22 0.3 1.77 1.81 0.77 4.5
 Hemoglobin (g/L) 69 54 72 45 98 66 101
 Platelets (×109/L) 13 16 6 8 21 6 16
Disease progression
 Karyotype 46,XY [20] 46,XY, [20] 46,XX,-7 [20] 46,XX [20] 46,XX [20] 46,XX [20] 46,XY [20]
 Bone marrow blasts (%) <5 <2 5 <5 <5 <5 <2
 ANC (×109/μl) 0.77 3.66 0.56 1.96 2.81 1.77 4.5
 Hemoglobin (g/L) 67 54 65 68 104 73 190
 Platelets (×109/L) 5 2 5 3 10 2 5
Time to progression (months) 9 6 9 9 6 7 6
Present status Alive Dead Alive Alive Alive Alive Alive

rhTPO, recombinant human thrombopoietin; ANC, absolute neutrophil count; Int-1, intermediate 1; Int-2, intermediate 2.