Table 3.
Clinical characteristics of patients who progressed during follow-up.
| rhTPO group | Non-rhTPO group | ||||||
|---|---|---|---|---|---|---|---|
| Patient 1 | Patient 2 | Patient 3 | Patient 4 | Patient 5 | Patient 6 | Patient 6 | |
| Age (years) | 41 | 58 | 67 | 46 | 62 | 52 | 48 |
| Sex | M | M | F | F | F | F | M |
| R-IPSS | Int-1 | Int-1 | Int-1 | Int-1 | Low | Int-1 | Low |
| Baseline | |||||||
| Karyotype | 46,XY [20] | 46,XY [20] | 46,XX [20] | 46,XX [20] | 46,XX [20] | 46,XX [20] | 46,XY [20] |
| Bone marrow blasts (%) | <5 | <5 | <2 | <5 | <5 | <5 | <2 |
| ANC (×109/μl) | 1.25 | 2.22 | 0.3 | 1.77 | 1.81 | 0.77 | 4.5 |
| Hemoglobin (g/L) | 69 | 54 | 72 | 45 | 98 | 66 | 101 |
| Platelets (×109/L) | 13 | 16 | 6 | 8 | 21 | 6 | 16 |
| Disease progression | |||||||
| Karyotype | 46,XY [20] | 46,XY, [20] | 46,XX,-7 [20] | 46,XX [20] | 46,XX [20] | 46,XX [20] | 46,XY [20] |
| Bone marrow blasts (%) | <5 | <2 | 5 | <5 | <5 | <5 | <2 |
| ANC (×109/μl) | 0.77 | 3.66 | 0.56 | 1.96 | 2.81 | 1.77 | 4.5 |
| Hemoglobin (g/L) | 67 | 54 | 65 | 68 | 104 | 73 | 190 |
| Platelets (×109/L) | 5 | 2 | 5 | 3 | 10 | 2 | 5 |
| Time to progression (months) | 9 | 6 | 9 | 9 | 6 | 7 | 6 |
| Present status | Alive | Dead | Alive | Alive | Alive | Alive | Alive |
rhTPO, recombinant human thrombopoietin; ANC, absolute neutrophil count; Int-1, intermediate 1; Int-2, intermediate 2.