REAGENT or RESOURCE	SOURCE	IDENTIFIER
Antibodies
Mouse anti-β-Amyloid, 1-16	BioLegend	catalog#803004; RRID: AB_2715854
Mouse anti-β-Amyloid, 17-24	BioLegend	catalog#800709; RRID: AB_2565325
Mouse anti-Rhodopsin, 1D4	Santa Cruz	catalog#sc-57432; RRID: AB_785511
Rabbit anti-GNAT1	Proteintech	catalog#55167-1-AP; RRID: AB_10858788
Rabbit anti-recoverin	Proteintech	catalog#10073-1-AP; RRID: AB_2178005
Rabbit anti-Opsin, blue	Millipore	catalog#AB5407; RRID: AB_177457
Rabbit anti-Opsin, Red/Green	Millipore	catalog#AB5405; RRID: AB_177456
Mouse anti-PKC alpha	Invitrogen	catalog#MA1-157; RRID: AB_2536865
Rabbit anti-PKC alpha	Abcam	catalog#ab32376; RRID: AB_777294
Rabbit anti-PSD95	Cell signaling technology	catalog#3450; RRID: AB_2292883
Mouse anti-CtBP2	BD Bioscience	catalog#612044; RRID: AB_399431
Mouse anti-RPE65	Novus	catalog#NB100-355; RRID: AB_350269
Rabbit anti-RPE65	Abcam	catalog#ab67042; RRID: AB_10673673
Rabbit anti-ZO-1	Invitrogen	catalog#617300; RRID: AB_2533938
Rabbit anti-P16-INK4A	Proteintech	catalog#10883-1-AP; RRID: AB_2078303
Mouse anti-p21	Santa Cruz	catalog#SC-6246; RRID: AB_628073
Rabbit anti-RIP3	Cell signaling technology	catalog#95702; RRID: AB_2721823
Mouse anti-RIP3	Santa Cruz	catalog#SC-374639; RRID: AB_10992232
Rabbit anti-RIP3 (phospho Thr231/Ser232)	Cell signaling technology	catalog#91702; RRID: N/A
Rabbit anti-MLKL (phospho S345)	Abcam	catalog#ab196436; RRID: AB_2687465
Rabbit anti-caspase 3	Cell signaling technology	catalog#9662; RRID: AB_331439
Rabbit anti-cleaved caspase 3	Cell signaling technology	catalog#9661; RRID: AB_2341188
Mouse anti-GAPDH	Millipore	catalog#MAB374; RRID: AB_2107445
Goat anti-mouse IgG (H+L) Alex Fluor 488	Cell signaling technology	catalog#4408; RRID: AB_10694704
Goat anti-mouse IgG (H+L) Alex Fluor 555	Cell signaling technology	catalog#4409; RRID: AB_1904022
Goat anti-rabbit IgG (H+L) Alex Fluor 488	Cell signaling technology	catalog#4412; RRID: AB_1904025
Goat anti-rabbit IgG (H+L) Alex Fluor 555	Cell signaling technology	catalog#4413; RRID: AB_10694110
HRP-conjugated anti-mouse IgG	Cell signaling technology	catalog#7076; RRID: AB_330924
HRP-conjugated anti-rabbit IgG	Cell signaling technology	catalog#7074; RRID: AB_2099233
Chemicals, peptides, and recombinant proteins
TRIzol Reagent	Invitrogen	catalog#15596018
DAPI	Invitrogen	catalog#D1306
Lectin PNA, Alex Fluor 488-conjugated	Invitrogen	catalog#L-21409
Curcumin	Sigma	catalog#C1386
Critical commercial assays
PrimeScript RT reagent kit	Takara	catalog#RR047A
SYBR Premix Ex Taq mix	Takara	catalog#RR420A
TUNEL	Roche	catalog#11684795910
Experimental models: Organisms/strains
Mouse: APP23	Jackson Laboratory	catalog#030504
Mouse: 5xFAD	Jackson Laboratory	catalog#034848
Mouse: APP NL-F knock-in	Provided by Dr. Takaomi Saido	N/A
Mouse: C57BL/6N	Charles river Laboratories	catalog#213
Oligonucleotides
Real-time PCR primers	This paper	N/A
Software and algorithms
ZEN software for LSM 800	Carl Zeiss	RRID: SCR_013672
GraphPad Prism 8.0	GraphPad Prism	RRID: SCR_002798
Image J	National Institutes of Health	RRID: SCR_003070
Clampfit 10.3	Molecular Devices	RRID: SCR_011323