TABLE 1.
Dysregulated proteins found in 5-FU/LV treatment group versus saline treatment group.
| UniProt id | Protein name | logFC | p value | Type | Location | Role |
|---|---|---|---|---|---|---|
| Q6DIB5 | Multiple epidermal growth factor-like domains protein 10 | 6.096875 | 0.004897 | Receptor | Plasma membrane | Autophagy and phagocytosis |
| E9Q9V3 | Nuclear receptor corepressor 2 | 4.050247 | 0.081694 | Coregulator | Nucleus, extracellular matrix | Part of nuclear receptor corepressor complex |
| Q9D7Y7 | Not available | 1.913693 | 8.1E-06 | Enzyme | ECM | Proteolysis |
| Q3UPW5 | Spermine oxidase | −4.11619 | 0.029856 | Enzyme | Cytoplasm | Apoptosis and polyamine metabolism |
| O88493 | Not available (Gene: Col6a3) | −4.75009 | 0.043115 | NA | Cell matrix and ECM | Cell adhesion, ECM organization |
| Q99K30 | Epidermal growth factor receptor kinase substrate 8-like protein 2 | −5.33513 | 0.025052 | Growth factor | Cytoplasm and plasma membrane | Actin binding, Rac/Rho signaling |
| O35161 | Cadherin EGF LAG seven-pass G-type receptor 1 | −6.12814 | 0.065984 | Receptor | Plasma membrane | GPCR, calcium ion binding |