Table 1.

Systematic reviews.

Study (13–16) (primary author, year)	Title	Identified studies	Included studies	Total number of included participants in each review
Backhouse, 2017	Early life risk factors for cerebrovascular disease.	19,180	29	23,356
Clancy, 2020	Neuropsychiatric symptoms associated with cerebral small vessel disease: a systematic review and meta-analysis.	7,119	81	21,730
Hamilton, 2020	Cognitive impairment in sporadic cerebral small vessel disease: a systematic review and meta-analysis.	8,562	69	6,908
Stewart, 2020	Associations between white matter hyperintensity burden, cerebral blood flow and transit time in small vessel disease: an updated meta-analysis.	783	30	3,396

Identified studies refer to those found by search after duplicates were removed. Included studies refer to those examined for data extraction. The number of included studies of each systematic review do not include duplicated studies or populations.