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Efficacy by use time of day. The efficacy was tested using linear mixed modeling (β coefficient was not standardized).
| Time of day | Estimate (SE) | t testa (df) | P value |
| Morning | 3.668345 (0.102629) | 35.744 (488.1) | <.001 |
| Afternoon | 2.754512 (0.225454) | 12.218 (120.1) | <.001 |
| Evening | 3.369924 (0.119686) | 28.156 (391.6) | <.001 |
| Overnight | 3.449696 (0.089454) | 38.564 (739.5) | <.001 |
aTests were two-tailed.
