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. 2021 Oct 27;12:665743. doi: 10.3389/fmicb.2021.665743

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Copyright © 2021 Aust, Benesova, Vidova, Coufalikova, Smetanova, Borek, Janku, Budinska, Klanova, Thon and Spacil.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Metabolic profile of VD and CD neonates. Correlated metabolites (p<0.01 and/or p<0.001) in VD neonates (A) and CD neonates (B) are marked in bold. Nonsignificant correlations are marked in gray. The microbial catabolites with significant correlations are highlighted in dark blue. The host metabolism products are marked in black. ArAT, aromatic amino acid aminotransferase, AAT, aromatic amino acid transferase, acdA, acyl-CoA dehydrogenase, AFMID, kynurenine formamidase, AO1, indole acetaldehyde oxidase, ECH2, enoyl-CoA hydratase-2, fldH, phenyl lactate dehydrogenase, fldBC, phenyl lactate dehydratase, IDO, indoleamine-2,3-dioxygenase, IaaH, indole acetamide hydrolase, IaaO, indole-3-acetic acid oxidase, KYNU, kynureninase, KAT, kynurenine amino transferase, MAO, monoamine oxygenase, NAT1, arylamine N-acetyltransferase 1, porB,C, pyruvate ferredoxin oxidoreductase B and C, PCD, pyruvate decarboxylase, TDO, tryptophan-2,3-dioxygenase, TMO, tryptophan-2-monooxygenase, TrD, tryptophan decarboxylase.