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. 2021 Oct 15;13(10):11413–11426.

Figure 5.

Figure 5

Cell lines and datasets evidence of GNA13 and TMZ sensitizations. A. Pearson’s correlation analysis shows that PRKACA is proportional to the expression of MGMT. B. qRT-PCR suggests that mRNA of PRKACA is downregulated in both GNA13-overexpressed cell lines of U251MG and U138MG. C. mRNA of MGMT decreases in GNA13-overexpressed U138MG cells. D. Result of immunoblot suggests that MGMT, total P65, p-P65 (Ser536) and PRKACA are significantly decreased in GNA13-overexpressed cells.