Table 3.
Comparison of the relative PPARα, HIF-1α, and VEGF mRNA levels in the liver tissues of the rats in each group (x̅ ± s)
| Group | n | PPARα mRNA | HIF-1α mRNA | VEGF mRNA |
|---|---|---|---|---|
| Control group | 10 | 0.98±0.11 | 0.26±0.05 | 0.43±0.04 |
| 4-week MD | 10 | 0.56±0.09① | 0.33±0.08① | 0.48±0.05① |
| 8-week MD | 10 | 0.42±0.08①,② | 0.44±0.07①,② | 0.54±0.06①,② |
| 12-week MD | 9 | 0.35±0.06①,②,③ | 0.52±0.08①,②,③ | 0.61±0.08①,②,③ |
| 16-week MD | 8 | 0.12±0.03①,②,③,④ | 0.62±0.11①,②,③,④ | 0.69±0.07①,②,③,④ |
| F value | 19.030 | 18.451 | 12.115 | |
| P value | < 0.001 | < 0.001 | < 0.001 |
①
P < 0.05, compared with the control group;
②
P < 0.05, compared with the 4-week model group;
③
P < 0.05, compared with the 8-week model group;
④
P < 0.05, compared with the 12-week model group.