Table 1.
Relationship between serum miR-506-3p expression and clinicopathologic features of patients with LC
| Clinicopathologic feature | n=92 | miR-506-3p | χ2 | P | |
|---|---|---|---|---|---|
|
| |||||
| High (n=46) | Low (n=46) | ||||
| Gender | 0.708 | 0.400 | |||
| Female | 40 | 22 (47.83) | 18 (39.13) | ||
| Male | 52 | 24 (52.17) | 28 (60.87) | ||
| Age (years) | 0.438 | 0.508 | |||
| <65 | 31 | 17 (36.96) | 14 (30.43) | ||
| ≥65 | 61 | 29 (63.04) | 32 (69.57) | ||
| Tumor size (cm) | 4.792 | 0.029 | |||
| ≤4 | 60 | 35 (76.09) | 25 (54.35) | ||
| >4 | 32 | 11 (23.91) | 21 (45.65) | ||
| TNM staging | 9.824 | 0.002 | |||
| I-II | 49 | 32 (69.57) | 17 (36.96) | ||
| III-IV | 43 | 14 (30.43) | 29 (63.04) | ||
| Differentiation degree | 5.887 | 0.015 | |||
| High/moderate differentiation | 61 | 36 (78.26) | 25 (54.35) | ||
| Low differentiation | 31 | 10 (21.74) | 21 (45.65) | ||
| Cirrhosis | 1.577 | 0.209 | |||
| No | 50 | 28 (60.87) | 22 (47.83) | ||
| Yes | 42 | 18 (39.13) | 24 (52.17) | ||
| HBV infection | 2.029 | 0.154 | |||
| No | 24 | 15 (32.61) | 9 (19.57) | ||
| Yes | 68 | 31 (67.39) | 37 (80.43) | ||
| AFP (μg/L) | 1.181 | 0.277 | |||
| <400 | 33 | 19 (41.30) | 14 (30.43) | ||
| ≥400 | 59 | 27 (58.70) | 32 (69.57) | ||