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B16F10 melanoma tumor at day 1 and day 7 in control untreated group and treated group. Mice were injected with 5 × 105 B16F10 cells suspended in 100 μL phosphate buffered saline. Once the tumor reached a size of 100 mm3, Control group was injected with normal saline while treatment group was injected with BMP inhibitor LDN193189 at a dose of 3 mg/kg body weight twice daily for ten consecutive days.
