(A) Illustration of the vancomycin and aptamer dual-recognition FRET assay for detection of S. aureus) (B) Fluorescence spectra of the FRET biosensor in the presence of S. aureus at varying concentrations (curves a-l correspond to 0, 10, 20, 30, 102, 103, 104, 105, 106, 107, 5 × 107 and 108 CFU/mL, respectively). (C) Calibration curve showing the linear relationship between fluorescence intensity and the logarithm of S. aureus concentration (log10N CFU/mL). Reproduced with permission from ref.75 Copyright 2018 American Chemical Society