Table 2. Serological Values of Liver and Kidney Function Parameters in Mice Treated with Halloysite Nanoclays^a.

			24 h			48 h
	units	reference	control	FHNTs	HNTs	control	FHNTs	HNTs
urea	mmol mL–1	8.87 ± 1.61	7.61 ± 1.13	5.1 ± 0.3	9.2 ± 0.7	8.5 ± 0.4	7.56 ± 0.4	8.21 ± 0.8
AST	U L–1	82.80 ± 39.85	79 ± 12.6	78 ± 4.6	70 ± 11.5	78 ± 9.6	78 ± 5.6	87 ± 7.3
ALT	U L–1	45.08 ± 16.11	35 ± 7.5	39 ± 2.3	30 ± 0.7	38 ± 6.8	40 ± 3.5	39 ± 3.7
creatinine	μM mL–1	10.73 ± 2.19	8.8 ± 1.2	9.1 ± 0.4	8.7 ± 0.1	8.8 ± 0.2	8.7 ± 0.2	9.1 ± 0.3
total protein	g L–1	52.30 ± 11.13	54 ± 6.4	54 ± 3.6	45 ± 2.3	56 ± 5.2	54 ± 5.3	53 ± 4.7
total bilirubin	μM mL–1	3.2 ± 1.2	2.37 ± 0.6	2.11 ± 0.3	2.23 ± 0.1	2.26 ± 0.1	2.3 ± 0.2	2.6 ± 0.2

^aThe mice were exposed to 5 mg Kg^–1 HNTs or FHNTs, and the values of urea, alanine aminotransferase (ALT), aspartate aminotransferase (AST), creatinine, total protein, and total bilirubin were determined at 48 h and 30 days post-treatment. All parameters were within the range reported as standard by the Charles River Laboratories.