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. 2021 Nov 11;21:363. doi: 10.1186/s12890-021-01708-y

Table 3.

Clinical responses of children with mild and severe adenovirus pneumonia according to the timing of BAL in the study

Variable Mild group (n = 70) Severe group (n = 64)
Early BAL
(n = 21)
Late BAL
(n = 49)
P value Early BAL
(n = 21)
Late BAL
(n = 43)
P value
Major indicators
Fever duration (days), median (range) 8(5–11) 10(5–18) 0.0287 11(7–19) 11(7–21) 0.2670
Length of stay (days), median (range 8(6–12) 11(6–19) 0.0006 12(9–29) 13(8–34) 0.2893
Minor indicators
Advanced life support
Mechanical ventilation, No. (%) 0(0.00) 0(0.00)  > 0.9999 5(23.81) 2(4.65) 0.0335
CBP, No. (%) 0(0.00) 0(0.00)  > 0.9999 0(0.00) 1(2.33)  > 0.9999
ECMO, no .(%) 0(0.00) 0(0.00)  > 0.9999 1(4.76) 2(4.65)  > 0.9999
Pulmonary sequelaes
PIBO, No. (%) 0(0.00) 1(2.04)  > 0.9999 5(23.81) 10(23.26)  > 0.9999
Bronchiectasis, no. (%) 0(0.00) 0(0.00)  > 0.9999 1(4.76) 3(6.98)  > 0.9999
Outcomes
Mortality, no. (%) 0(0.00) 0(0.00)  > 0.9999 1(4.76) 1(2.33)  > 0.9999

CBP: continuous blood purification; ECMO: extracorporeal membrane oxygenation; PIBO: post-infectious bronchiolitis

The bold means p < 0.05, which had statistical significance